Items Tagged ‘personal genomics’

November 13, 2014

Strand-Specific Analysis Shows Protein Binding at Replication Forks and PCNA Unloading from Lagging Strands when Forks Stall

By Center for Individualized Medicine Center for Individualized Medicine (@samuelsmith5209)

Zhiguo Zhang, Ph.D. and colleagues from the Center for Individualized Medicine, offer a new tool for genomic research, through a new method revealing genome-wide association of proteins with leading and lagging strands of DNA replication forks. This will provide a tool for studying the general replication-related processes and a specific mechanism that makes this possible. […]

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Tags: center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic, Genetics, genome, genome science, Genome Sequencing, Genomic


November 11, 2014

Individualizing Medicince 2014 Conference: Recap

By Center for Individualized Medicine Center for Individualized Medicine (@samuelsmith5209)

  Quoting “the great poet from Hibbing, Minn.,” genomics pioneer Richard Weinshilboum, M.D., captured the spirit of the third annual Individualizing Medicine Conference 2014: From Promise to Practice when he invoked the legendary Bob Dylan. “‘The times they are a changin’,” Dr. Weinshilboum said. The times are changing indeed. More than 750 physicians, researchers, scientists, medical […]

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Tags: Biobank, Bioethics, biomarker, biomarkers, cancer, center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic


November 10, 2014

What is Individualized Medicine?

By Center for Individualized Medicine Center for Individualized Medicine (@samuelsmith5209)

  What exactly does it mean when you hear the phrase “individualized medicine?”   Dr. Alexander Parker of the Center for Individualized Medicine at Mayo Clinic Florida, sat down with the Mayo Clinic Radio Health Minute to explain exactly what individualized medicine means.           _______

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Tags: Alex Parker, Alexander Parker, center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic, Genetics, genome, genome science


November 6, 2014

Genetic Markers for Alcoholism Recovery Discovered at Mayo Clinic

By Center for Individualized Medicine Center for Individualized Medicine (@samuelsmith5209)

  Post originally featured on Mayo Clinic’s News Network, written by Bob Nellis   In an international study, Mayo Clinic researchers and collaborators have identified genetic markers that may help in identifying individuals who could benefit from the alcoholism treatment drug acamprosate. The findings, published in the journal Translational Psychiatry, show that patients carrying these […]

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Tags: Alcoholism, Alcoholism Recovery, biomarker, biomarkers, center for individualized medicine, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic, Genetics, genome


November 4, 2014

Using Genomics to Treat Depression & Back Pain With the Right Drugs

By Center for Individualized Medicine Center for Individualized Medicine (@samuelsmith5209)

In a recent USA Today article, Assurex Health was featured for their new tool to analyze patient DNA and, within 36 hours, return a report (through a secure portal) back to providers detailing which medications are most likely to be effective based on their genome. The test is called GeneSight and has been around for […]

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Tags: Assurex, Assurex Health, center for individualized medicine, David Mrazek, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, Genetics, genome, genome science


October 30, 2014

The Future of Individualized Medicine at Mayo Clinic

By Center for Individualized Medicine Center for Individualized Medicine (@samuelsmith5209)

  Individualizing Medicine 2014: From Promise to Practice, was held in October in Rochester, focusing on how to translate the promise of genomic medicine into practice. Expert speakers, focused breakout sessions, real-life case studies and a poster session provided attendees with many opportunities to discover and discuss emerging topics in applied genomics. Speakers covered a […]

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Tags: Biobank, Bioethics, biomarker, biomarkers, center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic, Genetics


October 28, 2014

Findings Reveal Relationship with TP63 & p63 Protein Expression in Lung Adenocarcinoma

By Center for Individualized Medicine Center for Individualized Medicine (@samuelsmith5209)

    Using next-generation sequencing analysis of mate-pair DNA libraries, a group of researchers from the Center for Individualized Medicine recently identified novel chromosomal rearrangements involving TP63 in approximately 6% in peripheral T-cell lymphomas and demonstrated that these were associated with a poorer overall survival than lymphomas without these rearrangements. These rearrangements also were found in occasional B-cell […]

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Tags: Biobank, biomarker, biomarkers, cancer, center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic, Genetics


October 23, 2014

The Role of Ethics in Genomics

By Center for Individualized Medicine Center for Individualized Medicine (@samuelsmith5209)

    Jen McCormick, Ph.D., director of the Bioethics Program for the Center for Individualized Medicine at Mayo Clinic explains the goal of the Bioethics Program, which is to ensure that the Center for Individualized Medicine is aware of and responsibly addressing the ethical, legal, policy and social issues related to genomic research, translating genomic […]

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Tags: Bioethics, center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, Genetics, genome, genome science, Genome Sequencing, Genomic


October 15, 2014

Diet & Exercise Orthogonally Alter the Gut Microbiome

By Center for Individualized Medicine Center for Individualized Medicine (@samuelsmith5209)

  And Reveal Independent Associations With Anxiety & Cognition   The Microbiome team at the Center for Inidivdualized Medicine of Mayo Clinic recently published a paper that found that ingestion of a high-fat diet (HFD) and the resulting obese state can exert a multitude of stressors on the individual including anxiety and cognitive dysfunction. Though […]

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Tags: biomarker, biomarkers, center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic, Genetics, genome, genome science


October 14, 2014

A Mysterious Disease

By Center for Individualized Medicine Center for Individualized Medicine (@samuelsmith5209)

  Article Originally found at Mayo Clinic’s “You Are” Blog.   The genomic counselor brought good news — the Individualized Medicine Clinic team had found the culprit gene. Renata Burdell knew her son’s medical odyssey was finally over. “It has made such a huge difference,” Renata says. “We don’t have to keep wondering and going from […]

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Tags: Biobank, Bioethics, biomarker, biomarkers, cancer, center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, Genetics


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