Items Tagged &#8216;personalized medicine&#8217;

A collaborative team of scientists led by Mayo Clinic’s Center for Individualized Medicine has discovered 15 additional genetic mutations in the KCNK9 gene that cause a neurodevelopmental syndrome. Symptoms of the disorder range from speech and motor impairment to behavioral abnormalities, intellectual disability and distinctive facial features.

Study indicates gut microbiome, host gene affect gastrointestinal disorders

Tags: #neurological disorders, center for individualized medicine, Dr. Margot Cousin, gene sequencing, genomics, medical research, personalized medicine

May 19, 2022

In a new study published in Nature Microbiology, researchers demonstrated the power of integrating the microbiome and host gene expression data to provide insights into their combined role in gastrointestinal diseases. The microbiome consists of all microbes in the gut including bacteria, fungi, and viruses. This study focused on bacteria. “We identified a common set […]

Mayo patient with life-threatening multidrug-resistant infection treated with experimental phage therapy combined with surgery

Tags: center for individualized medicine, genomic medicine, individualized medicine, mayo clinic, medical research, personalized medicine

May 9, 2022

Mark Pearce, 61, was facing a possible limb amputation, even death, when a multidrug-resistant bacterial infection within his prosthetic hip replacement device started raging in his bloodstream. With his fever soaring to more than 105 degrees, Mark was taken by ambulance, that day in spring of 2020, to Mayo Clinic Hospital in Rochester, Minnesota.

Mayo Clinic researchers load CAR-T cells with oncolytic virus to treat solid cancer tumors

Tags: #bacterial infections, bacteria, bacteriophage therapy, center for individualized medicine, Dr. Gina Suh, Dr. Mark Pagnano, genomics, individualized medicine, infectious disease, personalized medicine, phage therapy

April 13, 2022

Researchers at Mayo Clinic’s Center for Individualized Medicine have devised an immunotherapy technique that combines chimeric antigen receptor-T cell therapy, or CAR-T cell therapy, with a cancer-killing virus to more effectively target and treat solid cancer tumors.

Mayo Clinic patient grateful after genetic test leads to unexpected, early detection of colon cancer

Tags: #CAR T-cell therapy, center for individualized medicine, Dr. Richard Vile, genomics, individualized medicine, medical research, oncolytic virus, personalized medicine

March 31, 2022

Alejandro Mirazo, 56, never imagined his genetic test results would reveal a hereditary link to cancer, or that his findings would potentially save his life. He had participated in a preemptive DNA research sequencing study for Mayo Clinic’s Center for Individualized Medicine in fall 2021 solely to contribute to medical research. As a Mexican American, he also wanted to add diversity to Mayo Clinic’s genomic dataset.

Study involving investigators from Mayo Clinic, Baylor College of Medicine applies drug-gene testing to improve patient care and reports outcomes

Tags: center for individualized medicine, DNA Testing, gene sequencing, Genetics, genomic medicine, medical research, personalized medicine

March 22, 2022

The results from the “Right Drug, Right Dose, Right Time: Using Genomic Data to Individualize Treatment” (RIGHT 10K) study strongly suggest that preemptive testing could benefit nearly every patient at some point, particularly when the testing extends beyond DNA variants already known to influence drug metabolism.

Mayo Clinic researchers use AI to predict antidepressant outcomes in youth

Tags: Baylor College of Medicine, center for individualized medicine, individualized medicine, mayo clinic, personalized medicine, pharmacogenomics

March 16, 2022

Mayo Clinic researchers have taken the first step in using artificial intelligence (AI) to predict early outcomes with antidepressants in children and adolescents with major depressive disorder, in a study published in The Journal of Child Psychology and Psychiatry.

Nanopore sequencing method rapidly detects, identifies antibiotic-resistant microbes, Mayo Clinic research shows

Tags: center for individualized medicine, genomics, individualized medicine, mayo clinic, medical research, personalized medicine

March 11, 2022

A growing number of people are dying from antibiotic-resistant infections. These infections are fueled by microbial species that are mutating to evade the drugs developed to destroy them. More than 1.2 million people worldwide died in 2019 from antibiotic-resistant infections. In response, a team of researchers from Mayo Clinic’s Center for Individualized Medicine has developed […]

Minnesota Partnership awards 5 collaborative research grants for 2022

Tags: antibiotic-resistant, bacteria, center for individualized medicine, Genetics, genomics, infectious disease, personalized medicine

January 13, 2022

The Minnesota Partnership for Biotechnology and Medical Genomics have announced their 2022 research awardees. This marks the partnership’s 18th year of spearheading new scientific ideas from Minnesota to improve the health of, and health care for, Minnesotans.

Mayo Clinic leads biorepository core for new nationwide research on long-term symptoms of COVID-19

Tags: center for individualized medicine, genomics, mayo clinic, medical research, personalized medicine

September 20, 2021

Mayo Clinic research is dedicated to finding solutions for patients who were infected with COVID-19 and the many affected by the long-term symptoms of COVID-19 ― what the National Institutes of Health (NIH) refers to as “long COVID” or post-acute sequelae. In response to great unmet patient need, the NIH launched a new research initiative […]