Items Tagged ‘pharmacogenomics’

September 30, 2021

Mayo Clinic M.D., Ph.D., Graduate Charts a Career Path Blending Science with Patient Care

By Susan Murphy Susan Murphy (@susanmurphy)

By: Julie Janovsky-Mason It was a day 10 years in the making for Jacqueline Zayas. On a recent Sunday afternoon, surrounded by classmates and a contingent of her loved ones, Dr. Zayas officially earned her medical degree as part of Mayo Clinic Alix School of Medicine’s class of 2021. “It was surreal, it seemed like this day […]

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Tags: Dr. Liewei Wang, Dr. Naveen Pereira, pharmacogenomics


March 23, 2021

Mayo Clinic researchers explore personalized approach to anti-obesity medications

By Colette Gallagher Colette Gallagher (@colettegallagher)

Individualized medicine initiatives mainly focus on rare diseases or cancer. Little has been attempted to individualize treatment for noncommunicable chronic diseases such as obesity — a chronic, relapsing disease, and a primary cause of Type 2 diabetes, fatty liver disease, cardiovascular disease and cancer. There are many obesity interventions, such as diets, devices, surgery and […]

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Tags: #Dr. Andres Acosta, #obesity, journal obesity, mayo clinic, Mayo Clinic Center for Individualized Medicine, pharmacogenomics, Precision Medicine


March 17, 2021

Data show clear benefit from genetic testing before prescribing antiplatelet therapy

By Susan Murphy Susan Murphy (@susanmurphy)

By Terri Malloy Pharmacogenomics is a valuable tool for health care providers to help prescribe the right drug for the right patient to enhance efficacy and avoid side effects. New research, funded in part by the National Heart, Lung and Blood Institute (NHLBI), shows  a clear advantage of genetic testing in helping health care providers […]

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Tags: antiplatelet, antiplatelet medication, coronary heart disease, Genetic Testing, pharmacogenomics


August 25, 2020

Largest pharmacogenetics clinical trial in cardiology shows potential benefit in individualized approach to anti-platelet therapy

By Susan Murphy Susan Murphy (@susanmurphy)

By Terri Malloy Heart patients who undergo percutaneous coronary intervention (PCI) or stent placement― nonsurgical procedures to improve blood flow to the heart ― are typically prescribed anti-platelet therapy to avoid blood clots that can lead to a heart attack or stroke. New research from the international TAILOR-PCI trial, the largest pharmacogenetics clinical trial in […]

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Tags: #cardiology, Cardiovascular Disease, individualized medicine, pharmacogenomics


March 10, 2020

How pharmacogenomics can improve the lives of persons living with HIV

By Susan Murphy Susan Murphy (@susanmurphy)

By Jessica Fenske Life with HIV typically means using any number of medications to control the virus. But not all medications are the same or act the same way in different people. Mayo researchers are zeroing in on a new test to help patients fine-tune their treatments. While there is no cure for HIV, there […]

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Tags: pharmacogenomics, Research


September 25, 2019

The BEAUTY of it: award recognizes personalized medicine approach for breast cancer

By Barbara J. Toman Barbara J. Toman (@barbaratoman)

A Mayo Clinic research team supported by the Center for Individualized Medicine is making significant breakthroughs — and gaining recognition for them. The Breast Cancer Genome-Guided Therapy (BEAUTY) project has received the 2019 Mayo Clinic Team Science Award, given for interdisciplinary work that substantially advances Mayo’s research. The award cites BEAUTY’s discoveries about breast tumor […]

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Tags: #targeted therapies, BEAUTY trial, breast cancer, center for individualized medicine, chemotherapy, chemotherapy-resistant breast cancer, Dr. Judy Boughey, Dr. Liewei Wang, Dr. Matthew Goetz, Genetics, genomics, individualized medicine


July 25, 2019

Antoni Ribas, M.D., Ph.D. – leading melanoma researcher to speak at #CIMCON19

By Sharon Rosen Sharon Rosen (@sharonhrosen)

Article by Sara Damore Melanoma is an aggressive skin cancer caused by extensive sun exposure and the fifth most common cancer in the U.S. If detected and treated early, the survival rates for melanoma are high (98%). However, once the cancer spreads to other areas of the body, survival rates for malignant melanoma drop dramatically […]

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Tags: #CIMCon19, #skin cancer, BRAF gene, center for individualized medicine, Dr. Antoni Ribas, geenetics, genomics, Herpes virus, immunotherapy, individualized medicine, mayo clinic, Melanoma


July 9, 2019

Mayo experts provide insights into how genes affect medication response

By Sharon Rosen Sharon Rosen (@sharonhrosen)

Pharmacogenomics – how a person’s genes affect medication response – is touching virtually every area of medical care.  Findings from the Mayo Clinic RIGHT study (Right Drug, Right Dose, Right Time–Using Genomic Data to Individualize Treatment) showed that 99% of participants had at least one genetic variant that may affect their response to medications.    […]

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Tags: #addiction, #anti-seizure medication, #Center for Individualized Mediicine, #Dr. Lauren Cornell, #Dr. Sanjay Bagaria, #Dr. William Freeman, #Dr. William Palmer, #drug-gene interactions, #epilepsy, #estrogen receptor positive breast cancer, #medical education, #neurological diseases


April 23, 2019

Editorial: Why DNA sequencing is an effective tool for patient care

By Colette Gallagher Colette Gallagher (@colettegallagher)

By Keith Stewart, M.B., CH.B. For the past 30 years, I’ve been fortunate enough to work with and help many patients. But over that time, I’ve also met people who did not respond to therapy or had significant side effects, while others had marvelous responses. Cases like these show a clear need for personalized medicine. […]

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Tags: #rare and undiagnosed diseases, DNA Sequencing, Dr. Keith Stewart, Mayo Clinic Center for Individualized Medicine, pharmacogenomics, undiagnosed disease


November 12, 2018

Novel data-driven approach for precision medicine

By Colette Gallagher Colette Gallagher (@colettegallagher)

Thousands of patients’ tumors have been sequenced in the past decade, yielding a rich source of data on the changes associated with the cancer development and treatment response. However, there are no validated methods that are used in the clinic to select the best therapy. Today, Mayo Clinic researchers report an omics-guided (comprehensive) drug prioritization […]

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Tags: #Dr. Krishna Kalari, Dr. Judy Boughey, Dr. Liewei Wang, Dr. Matthew Goetz, Mayo Clinic Center for Individualized Medicine, personal genomics, pharmacogenomics


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