Items Tagged ‘pharmacogenomics’
March 22, 2022
The results from the “Right Drug, Right Dose, Right Time: Using Genomic Data to Individualize Treatment” (RIGHT 10K) study strongly suggest that preemptive testing could benefit nearly every patient at some point, particularly when the testing extends beyond DNA variants already known to influence drug metabolism.
Tags: Baylor College of Medicine, center for individualized medicine, individualized medicine, mayo clinic, personalized medicine, pharmacogenomics
September 30, 2021
Mayo Clinic M.D., Ph.D., Graduate Charts a Career Path Blending Science with Patient Care
By Susan Murphy 
By: Julie Janovsky-Mason It was a day 10 years in the making for Jacqueline Zayas. On a recent Sunday afternoon, surrounded by classmates and a contingent of her loved ones, Dr. Zayas officially earned her medical degree as part of Mayo Clinic Alix School of Medicine’s class of 2021. “It was surreal, it seemed like this day […]
March 23, 2021
Mayo Clinic researchers explore personalized approach to anti-obesity medications
Individualized medicine initiatives mainly focus on rare diseases or cancer. Little has been attempted to individualize treatment for noncommunicable chronic diseases such as obesity — a chronic, relapsing disease, and a primary cause of Type 2 diabetes, fatty liver disease, cardiovascular disease and cancer. There are many obesity interventions, such as diets, devices, surgery and […]
Tags: #Dr. Andres Acosta, #obesity, journal obesity, mayo clinic, Mayo Clinic Center for Individualized Medicine, pharmacogenomics, Precision Medicine
March 17, 2021
Data show clear benefit from genetic testing before prescribing antiplatelet therapy
By Susan Murphy
By Terri Malloy Pharmacogenomics is a valuable tool for health care providers to help prescribe the right drug for the right patient to enhance efficacy and avoid side effects. New research, funded in part by the National Heart, Lung and Blood Institute (NHLBI), shows a clear advantage of genetic testing in helping health care providers […]
Tags: antiplatelet, antiplatelet medication, coronary heart disease, Genetic Testing, pharmacogenomics
August 25, 2020
By Susan Murphy
By Terri Malloy Heart patients who undergo percutaneous coronary intervention (PCI) or stent placement― nonsurgical procedures to improve blood flow to the heart ― are typically prescribed anti-platelet therapy to avoid blood clots that can lead to a heart attack or stroke. New research from the international TAILOR-PCI trial, the largest pharmacogenetics clinical trial in […]
Tags: #cardiology, Cardiovascular Disease, individualized medicine, pharmacogenomics
March 10, 2020
How pharmacogenomics can improve the lives of persons living with HIV
By Susan Murphy
By Jessica Fenske Life with HIV typically means using any number of medications to control the virus. But not all medications are the same or act the same way in different people. Mayo researchers are zeroing in on a new test to help patients fine-tune their treatments. While there is no cure for HIV, there […]
Tags: pharmacogenomics, Research
September 25, 2019
The BEAUTY of it: award recognizes personalized medicine approach for breast cancer
A Mayo Clinic research team supported by the Center for Individualized Medicine is making significant breakthroughs — and gaining recognition for them. The Breast Cancer Genome-Guided Therapy (BEAUTY) project has received the 2019 Mayo Clinic Team Science Award, given for interdisciplinary work that substantially advances Mayo’s research. The award cites BEAUTY’s discoveries about breast tumor […]
Tags: #targeted therapies, BEAUTY trial, breast cancer, center for individualized medicine, chemotherapy, chemotherapy-resistant breast cancer, Dr. Judy Boughey, Dr. Liewei Wang, Dr. Matthew Goetz, Genetics, genomics, individualized medicine
July 25, 2019
Antoni Ribas, M.D., Ph.D. – leading melanoma researcher to speak at #CIMCON19
By Sharon Rosen 
Article by Sara Damore Melanoma is an aggressive skin cancer caused by extensive sun exposure and the fifth most common cancer in the U.S. If detected and treated early, the survival rates for melanoma are high (98%). However, once the cancer spreads to other areas of the body, survival rates for malignant melanoma drop dramatically […]
Tags: #CIMCon19, #skin cancer, BRAF gene, center for individualized medicine, Dr. Antoni Ribas, geenetics, genomics, Herpes virus, immunotherapy, individualized medicine, mayo clinic, Melanoma
July 9, 2019
Mayo experts provide insights into how genes affect medication response
By Sharon Rosen
Pharmacogenomics – how a person’s genes affect medication response – is touching virtually every area of medical care. Findings from the Mayo Clinic RIGHT study (Right Drug, Right Dose, Right Time–Using Genomic Data to Individualize Treatment) showed that 99% of participants had at least one genetic variant that may affect their response to medications. […]
Tags: #addiction, #anti-seizure medication, #Center for Individualized Mediicine, #Dr. Lauren Cornell, #Dr. Sanjay Bagaria, #Dr. William Freeman, #Dr. William Palmer, #drug-gene interactions, #epilepsy, #estrogen receptor positive breast cancer, #medical education, #neurological diseases
April 23, 2019
Editorial: Why DNA sequencing is an effective tool for patient care
By Keith Stewart, M.B., CH.B. For the past 30 years, I’ve been fortunate enough to work with and help many patients. But over that time, I’ve also met people who did not respond to therapy or had significant side effects, while others had marvelous responses. Cases like these show a clear need for personalized medicine. […]
Tags: #rare and undiagnosed diseases, DNA Sequencing, Dr. Keith Stewart, Mayo Clinic Center for Individualized Medicine, pharmacogenomics, undiagnosed disease