Items Tagged ‘Research’
January 13, 2021
Convalescent plasma antibody levels and the risk of death from COVID-19
By Susan Murphy 
By Bob Nellis| ROCHESTER, Minn. – Mayo Clinic researchers and collaborators have found an association between administration of convalescent plasma containing high antibodies and lower mortality rates for hospitalized patients with COVID-19 who are not on ventilators. The findings, “Convalescent Plasma Antibody Levels and the Risk of Death from Covid-19,” appear today in the New […]
December 24, 2020
2020 Mayo Clinic Precision Medicine Advances
By Susan Murphy
This year, Mayo Clinic’s Center for Individualized Medicine was at the forefront of COVID-19 research, working to unravel the complexities of the virus in order to discover life-saving treatments and prevention — from testing to building a pandemic response biobank to identifying COVID-19 strains within individual patients. But even in the midst of the pandemic, […]
Tags: artificial intelligence, Cancer Research, Genetics, genomics, individualized medicine, multi-omics, Research
November 16, 2020
A World in a Grain of Sand: New Discoveries in Kidney Stones
The Mayo Clinic and Illinois Alliance for Technology-Based Healthcare has a 10-year history of collaborations that led to important new medical knowledge and treatments. Now, joint research at Mayo Clinic and the University of Illinois at Urbana-Champaign is suggesting new possibilities for treating and preventing painful kidney stones. “Our research collaboration with the University of […]
Tags: Dr. Nicholas Chia, kidney stones, Mayo Clinic Center for Individualized Medicine, Microbiome Program, Research
November 2, 2020
Mayo Clinic study finds 1 in 8 patients with cancer harbor inherited genetic mutations
By Susan Murphy
Genetic testing can uncover inherited genetic mutations, and could individualize cancer therapies, improve survival, manage cancer in loved ones and push the boundaries of precision medicine. In a new study published in JAMA Oncology, scientists with Mayo Clinic’s Center for Individualized Medicine conducted genetic testing in more than 3,000 patients who were diagnosed with cancer […]
Tags: cancer genomics, Cancer Research, Genetic Testing, Genetics, Individualizing Medicine, Inherited cancer, Research
October 20, 2020
Toxic Cellular Ooze Linked to Biological Age, Disease and Disability
By Susan Murphy
By Sara Tiner Cells in the body usually do what they’re told. In response to cues, cells divide, grow, shrink or die as needed. But there are some cells that start to ignore the body’s order to expire: senescent cells. Sometimes called “zombie cells” for their undead lingering, senescent cells have triggered the body’s kill […]
Tags: biomarkers, cells, individualized medicine, Research
August 12, 2020
Could population genetic screening improve public health?
Hereditary BRCA-related breast and ovarian cancer, Lynch syndrome and familial hypercholesterolemia are estimated to be relatively prevalent in the general population but poorly found using traditional risk screening. In a typical medical practice, genetic testing for these conditions is based on personal or family history, ethnic background or other demographic characteristics, that may not always […]
Tags: #Familial hypercholesterolemia, breast cancer, Dr. Matthew Ferber, lynch syndrome, mayo clinic, Mayo Clinic Center for Individualized Medicine, ovarian cancer, population health genomics, Research
June 29, 2020
Mayo Clinic COVID-19 modeling for patients, communities
By Susan Murphy
By Elizabeth Zimmermann| Discovery’s Edge Building predictions based on a set of variables, an effort called modeling, has gotten a lot of airtime during the COVID-19 pandemic. Understanding both the virus and the disease, including how it spreads and its impacts on population health, guides advice to the public on how to stay safe. At […]
June 23, 2020
Controversial CRISPR case in China raises stakes for how genetic research is conducted
By Jay Furst
Mayo Clinic colleagues take a close look at what went wrong with the process in China and how it challenged the implicit “social contract” between science and society In November 2018, a Chinese biophysicist used a gene-editing technique known by the acronym CRISPR to edit human embryos for reproductive purposes, and he announced the birth […]
June 12, 2020
Mayo Clinic launches neutralizing antibody test to advance COVID-19 therapies
By Ginger Plumbo A new COVID-19 antibody test developed by researchers in Mayo Clinic Center for Individualized Medicine and Advanced Diagnostic Laboratory explores whether people gain immunity after being infected, and can fight off the novel virus if it comes back. The new SARS-CoV-2 neutralizing antibody test supports the national Expanded Access Program for Convalescent Plasma and […]
June 8, 2020
Unanswered Questions Drive Convalescent Plasma Research
By Susan Murphy
By Sara Tiner On Saturday, March 14, in southwest Wisconsin, a woman was working in her yard, raking and clearing the first spring weeds. She coughed a bit during the day, and felt some achiness in her lower back, some fatigue. It was in the high 30s that day, but she was warm when she […]