Items Tagged ‘Research’

March 18, 2021

New Framework Leads to Surprise in Early Human Development

By Sara Tiner Sara Tiner (@saratiner)

Mayo Clinic and Yale University scientists have developed a minimally invasive process for studying early cell development in a living person. The team reconstructed the cell history of two adult volunteers from just after cell fertilization. They found that in the first cell divide — 29 years earlier for one volunteer and 66 years earlier […]

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Tags: cells, genome, individualized medicine, Research


January 19, 2021

Mayo researchers explore genetics behind COVID-19 outcomes

By Susan Murphy Susan Murphy (@susanmurphy)

Some patients with COVID-19 experience severe complications, such as organ damage, shortness of breath, neurological impairment and chronic fatigue. A team of researchers within Mayo Clinic Center for Individualized Medicine is contributing to the global effort of using advanced genetic sequencing to find out which genes influence disease outcomes. “Our findings will be crucial in […]

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Tags: covid-19, Genetic Testing, Genetics, Genomic Research, individualized medicine, Research


January 13, 2021 · Leave a Comment

Convalescent plasma antibody levels and the risk of death from COVID-19

By Susan Murphy Susan Murphy (@susanmurphy)

By Bob Nellis| ROCHESTER, Minn. – Mayo Clinic researchers and collaborators have found an association between administration of convalescent plasma containing high antibodies and lower mortality rates for hospitalized patients with COVID-19 who are not on ventilators. The findings, “Convalescent Plasma Antibody Levels and the Risk of Death from Covid-19,” appear today in the New […]

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Tags: covid-19, Research


December 24, 2020

2020 Mayo Clinic Precision Medicine Advances

By Susan Murphy Susan Murphy (@susanmurphy)

This year, Mayo Clinic’s Center for Individualized Medicine was at the forefront of COVID-19 research, working to unravel the complexities of the virus in order to discover life-saving treatments and prevention — from testing to building a pandemic response biobank to identifying COVID-19 strains within individual patients. But even in the midst of the pandemic, […]

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Tags: artificial intelligence, Cancer Research, Genetics, genomics, individualized medicine, multi-omics, Research


November 16, 2020 · Leave a Comment

A World in a Grain of Sand: New Discoveries in Kidney Stones

By Colette Gallagher Colette Gallagher (@colettegallagher)

The Mayo Clinic and Illinois Alliance for Technology-Based Healthcare has a 10-year history of collaborations that led to important new medical knowledge and treatments. Now, joint research at Mayo Clinic and the University of Illinois at Urbana-Champaign is suggesting new possibilities for treating and preventing painful kidney stones. “Our research collaboration with the University of […]

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Tags: Dr. Nicholas Chia, kidney stones, Mayo Clinic Center for Individualized Medicine, Microbiome Program, Research


November 2, 2020 · Leave a Comment

Mayo Clinic study finds 1 in 8 patients with cancer harbor inherited genetic mutations

By Susan Murphy Susan Murphy (@susanmurphy)

Genetic testing can uncover inherited genetic mutations, and could individualize cancer therapies, improve survival, manage cancer in loved ones and push the boundaries of precision medicine. In a new study published in JAMA Oncology, scientists with Mayo Clinic’s Center for Individualized Medicine conducted genetic testing in more than 3,000 patients who were diagnosed with cancer […]

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Tags: cancer genomics, Cancer Research, Genetic Testing, Genetics, Individualizing Medicine, Inherited cancer, Research


October 20, 2020 · Leave a Comment

Toxic Cellular Ooze Linked to Biological Age, Disease and Disability

By Susan Murphy Susan Murphy (@susanmurphy)

By Sara Tiner Cells in the body usually do what they’re told. In response to cues, cells divide, grow, shrink or die as needed. But there are some cells that start to ignore the body’s order to expire: senescent cells. Sometimes called “zombie cells” for their undead lingering, senescent cells have triggered the body’s kill […]

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Tags: biomarkers, cells, individualized medicine, Research


August 12, 2020 · Leave a Comment

Could population genetic screening improve public health?

By Colette Gallagher Colette Gallagher (@colettegallagher)

Hereditary BRCA-related breast and ovarian cancer, Lynch syndrome and familial hypercholesterolemia are estimated to be relatively prevalent in the general population but poorly found using traditional risk screening. In a typical medical practice, genetic testing for these conditions is based on personal or family history, ethnic background or other demographic characteristics, that may not always […]

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Tags: #Familial hypercholesterolemia, breast cancer, Dr. Matthew Ferber, lynch syndrome, mayo clinic, Mayo Clinic Center for Individualized Medicine, ovarian cancer, population health genomics, Research


June 29, 2020 · Leave a Comment

Mayo Clinic COVID-19 modeling for patients, communities

By Susan Murphy Susan Murphy (@susanmurphy)

By Elizabeth Zimmermann| Discovery’s Edge Building predictions based on a set of variables, an effort called modeling, has gotten a lot of airtime during the COVID-19 pandemic. Understanding both the virus and the disease, including how it spreads and its impacts on population health, guides advice to the public on how to stay safe. At […]

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Tags: covid-19, Research


June 23, 2020 · Leave a Comment

Controversial CRISPR case in China raises stakes for how genetic research is conducted

By Jay Furst Jay Furst (@jayfurst)

Mayo Clinic colleagues take a close look at what went wrong with the process in China and how it challenged the implicit “social contract” between science and society In November 2018, a Chinese biophysicist used a gene-editing technique known by the acronym CRISPR to edit human embryos for reproductive purposes, and he announced the birth […]

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Tags: CRISPR, genomics, Research


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