June 23, 2020
Controversial CRISPR case in China raises stakes for how genetic research is conducted
By Jay Furst
Mayo Clinic colleagues take a close look at what went wrong with the process in China and how it challenged the implicit “social contract” between science and society In November 2018, a Chinese biophysicist used a gene-editing technique known by the acronym CRISPR to edit human embryos for reproductive purposes, and he announced the birth […]
June 12, 2020
Mayo Clinic launches neutralizing antibody test to advance COVID-19 therapies
By Ginger Plumbo A new COVID-19 antibody test developed by researchers in Mayo Clinic Center for Individualized Medicine and Advanced Diagnostic Laboratory explores whether people gain immunity after being infected, and can fight off the novel virus if it comes back. The new SARS-CoV-2 neutralizing antibody test supports the national Expanded Access Program for Convalescent Plasma and […]
June 8, 2020
Unanswered Questions Drive Convalescent Plasma Research
By Susan Murphy
By Sara Tiner On Saturday, March 14, in southwest Wisconsin, a woman was working in her yard, raking and clearing the first spring weeds. She coughed a bit during the day, and felt some achiness in her lower back, some fatigue. It was in the high 30s that day, but she was warm when she […]
June 1, 2020
Seeing cancer, but not through a microscope
By Susan Murphy
By Marla Broadfoot, Ph.D. / Discovery’s Edge Toward the end of the 19th century, a French doctor named Ernest Besnier coined the term “biopsy,” combining the Greek bios (life) and opsis (a sight). In the decades since, clinicians have performed countless biopsies on suspected cancer patients, all to catch a glimpse of cells on the […]
Tags: cancer, Cancer Research, Genetics, Research
April 27, 2020
Noninvasive test may help some patients with melanoma avoid lymph node biopsy
By Jay Furst
A Mayo Clinic-led research team has developed a test for patients who have melanoma, the most serious form of skin cancer, that shows whether they’re at risk of the cancer spreading to other areas of the body. The research, described in the journal JCO Precision Oncology, could allow some patients at low risk of metastasis […]
March 13, 2020
Mayo Clinic working to mitigate impacts of COVID-19 (coronavirus) pandemic
By Susan Murphy
By Mayo Clinic News Network In response to the progression of COVID-19 (coronavirus), Mayo Clinic is committed to helping you stay informed. Here are some of the ways our researchers, physicians and staff are working relentlessly to mitigate the impacts of this pandemic, and steps you and your family can take to stay healthy. Mayo […]
March 10, 2020
How pharmacogenomics can improve the lives of persons living with HIV
By Susan Murphy
By Jessica Fenske Life with HIV typically means using any number of medications to control the virus. But not all medications are the same or act the same way in different people. Mayo researchers are zeroing in on a new test to help patients fine-tune their treatments. While there is no cure for HIV, there […]
Tags: pharmacogenomics, Research
March 5, 2020
Rise in kidney cancer spurs Mayo researcher’s urgency to improve patient outcomes
As a trainee oncologist, Thai Ho, M.D., Ph.D., was struck by the number of people he saw at a veterans’ hospital with kidney cancer. “It’s one of the cancers that disproportionately affects military personnel, possibly due to environmental exposures,” he says. The results can be devastating. “On average, patients with kidney cancer lose 12 years […]
Tags: cancer, Cancer Research, Epigenetic research, Epigenomics, kidney cancer, Research
January 14, 2019
Using brain organoids to uncover causes of neuropsychiatric disorders
Mayo Clinic and Yale University collaborated in a study published in Science to create a new model for studying neuropsychiatric disorders in early human brain development. This unique collaboration brought together Mayo Clinic’s team-based, patient-centered research with Yale researchers to discover and analyze the genetic mechanisms that may cause these disorders. The Mayo Clinic team, […]
Tags: Alexej Abyzov, autism, brain organoids, mayo clinic, Mayo Clinic Center for Individualized Medicine, neuropsychiatric disorders, Ph.D., Research, Yale University
November 7, 2017
Twenty-first century precision medicine cancer care
By Sharon Rosen
As genomic sequencing has become faster and less expensive, physicians have used this new technology to guide and manage care for patients with cancer. Genomic testing, also known as genomic profiling, was initially used for patients with advanced cancer when standard therapy failed. The goal of the testing was to identify unique genetic characteristics of […]
Tags: #cancer treatment, #Dr. Mitesh Borad, #genetic panel tests, #Genomic profiling, #targeted therapies, #tissue biopsy, #tumor sequencing, cancer, center for individualized medicine, Dr. Patricia LoRusso, mayo clinic, Mayo Clinic Proceedings