Items Tagged ‘RNA’

July 31, 2015

Mayo Clinic Study Uncovers Key Differences Among ALS Patients

By Jeff Briggs Jeff Briggs (@JeffreyBriggs)

ALS, or amyotrophic laterals sclerosis, is a devastating disease for thousands of people in the country. Rapidly progressive, invariably fatal, ALS is a neurodegenerative disease that affects nerve cells in the brain and the spinal cord. It attacks the nerve cells responsible for controlling voluntary muscles (muscle action we are able to control, such as […]

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Tags: ALS, ALS Ice Bucket Challenge, amyotrophic laterals sclerosis, center for individualized medicine, Dr. Hu Li, Dr. Leonard Petrucelli, genomic medicine, Lou Gehrig's disease, Mayo Clinic Florida, RNA, RNA defects

November 21, 2013

ASCL1 And RET Expression Defines Clinically Relevant Subgroup Of Lung Adenocarcinoma

By Center for Individualized Medicine Center for Individualized Medicine (@samuelsmith5209)

A recent publication, featuring the Director of the Biomarker Discovery Program at the Center for Individualized Medicine at Mayo Clinic, George Vasmatzis, examining the role of ASCL1 in the neuroendocrine differentiation of lung adenocarcinoma. The clinical significance of neuroendocrine differentiation in lung adenocarcinoma, and the most appropriate biomarkers for this assessment, has long been debated. In the […]

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Tags: ASCL1, biomarker, Biomarker Discovery, Biomarker Discovery Program, cancer, center for individualized medicine, chromogranin, DNA, George Vasmatzis, immunohistochemical, individualized medicine, Lung Cancer

September 12, 2013

New Publication from Center for Individualized Medicine

By AJ Montpetit AJ Montpetit (@ajmontpetit)

Novel TRAF1-ALK fusion identified by deep RNA sequencing of anaplastic large cell lymphoma  Abstract Chromosomal translocations leading to expression of abnormal fusion proteins play a major role in the pathogenesis of various hematologic malignancies. The recent development of high-throughput, “deep” sequencing has allowed discovery of novel translocations leading to a rapid increase in understanding these diseases. Translocations […]

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Tags: center for individualized medicine, gene sequencing, genome, Genomic Sequencing, genomics, George Vasmatzis, individualized medicine, personalized medicine, RNA

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