Items Tagged ‘#targeted therapies’

September 25, 2019

The BEAUTY of it: award recognizes personalized medicine approach for breast cancer

By Barbara J. Toman Barbara J. Toman

A Mayo Clinic research team supported by the Center for Individualized Medicine is making significant breakthroughs — and gaining recognition for them. The Breast Cancer Genome-Guided Therapy (BEAUTY) project has received the 2019 Mayo Clinic Team Science Award, given for interdisciplinary work that substantially advances Mayo’s research. The award cites BEAUTY’s discoveries about breast tumor […]

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Tags: #targeted therapies, BEAUTY trial, breast cancer, center for individualized medicine, chemotherapy, chemotherapy-resistant breast cancer, Dr. Judy Boughey, Dr. Liewei Wang, Dr. Matthew Goetz, Genetics, genomics, individualized medicine


August 15, 2019

Shaping the landscape of cancer care with precision therapies

By Sharon Rosen Sharon Rosen

Article by Sara Damore Jeffrey Tyner, Ph.D., associate professor in the Department of Cell & Developmental Biology at Oregon Health & Science University, will join several precision cancer care leaders from across the country at the annual Individualizing Medicine Conference. Dr. Tyner will present “Precision Therapy through Functional Genomics in Hematologic Malignancies.” Dr. Tyner’s research […]

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Tags: #acute myeloid leukemia, #CIMCon19, #Dr. Jeffrey Tyner, #Functional Genomics, #targeted therapies, blood cancers, center for individualized medicine, genomics, hematolgic malignancies, Individualizing Medicine Conference 2019, mayo clinic, Oregon Health and Science University


June 10, 2019

Meet William Bobo, M.D. – taking the guesswork out of finding the right depression therapy

By Sharon Rosen Sharon Rosen

Depression can touch every aspect of a person’s life – affecting the way they think, feel and behave. It is also the leading medical condition for those who complete suicide. Getting the right therapy is crucial. But for patients suffering from the disorder, finding an effective treatment often involves trial and error. That’s because it […]

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Tags: #Artificial Intelligence, #Center for Individualized Mediicine, #Dr. Arjun Athreya, #Dr. William Bobo, #individualized mediicne, #Mayo Clinic and Illinois Alliance for Technology-Based Healthcare, #mood disorders, #predictive algorithm, #selective serotonin reuptake inhibitors, #targeted therapies, #Treatment response, antidepressants


May 7, 2019

Targeting bile duct cancer – meet Mitesh Borad, M.D.

By Sharon Rosen Sharon Rosen

The search for treatment targets for patients with bile duct cancer, also known as cholangiocarcinoma, has taken a 360 degree turn, offering new hope for patients. That’s according to Mitesh Borad, M.D., deputy director for Center for Individualized Medicine Biomarker Discovery Program at Mayo Clinic’s Arizona campus, Dr. Borad and his colleagues are using new […]

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Tags: #Dr. Mitesh Borad, #liver cancer, #targeted therapies, bile duct cancer, Biomarker Discovery Program, cholangiocarcinoma, fibroblast growth factor receptor (FGFR) inhibitors, Genetic Testing, genomics, Liquid biopsy, mayo clinic, Mayo Clinic Center for Individualized Medicine


July 2, 2018

A clearer picture: new imaging technologies advance diagnosis, individualized care

By Sharon Rosen Sharon Rosen

When treating patients with cancer, one of the most challenging questions that physicians face is determining whether a tumor should be surgically removed immediately, or if it can be monitored over the course of time without performing surgery. Imaging tests – such as a CT scan or MRI – are essential tools that clinicians rely […]

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Tags: #Artificial Intelligence, #CIMCon18, #disease prediction, #Dr. Gabriel Krestin, #Dr. Kiaran McGee, #imaging biomarkers, #imaging tests, #Individualizing Medicine 2018: Advancing Care Through Genomics, #targeted therapies, individualized medicine, mayo clinic


February 13, 2018

New international practice guidelines for using tamoxifen to treat breast cancer

By Colette Gallagher Colette Gallagher

An international group of clinicians and scientists representing the Clinical Pharmacogenetics Implementation Consortium (CPIC) published the first-ever clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy in Clinical Pharmacology and Therapeutics. Tamoxifen is a hormonal agent used for the prevention and treatment of premenopausal and postmenopausal breast cancer that is estrogen receptor positive. […]

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Tags: #CIMCon18, #clinical guidelines, #Clinical Pharmacogenetics Implementation Consortium, #CYP2D6 geneotype, #estrogen receptor positive breast cancer, #tamoxifen, #targeted therapies, breast cancer, center for individualized medicine, DNA Sequencing, Dr. Matthew Goetz, Genetic Testing


November 7, 2017

Twenty-first century precision medicine cancer care

By Sharon Rosen Sharon Rosen

As genomic sequencing has become faster and less expensive, physicians have used this new technology to guide and manage care for patients with cancer. Genomic testing, also known as genomic profiling, was initially used for patients with advanced cancer when standard therapy failed. The goal of the testing was to identify unique genetic characteristics of […]

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Tags: #cancer treatment, #Dr. Mitesh Borad, #genetic panel tests, #Genomic profiling, #targeted therapies, #tissue biopsy, #tumor sequencing, cancer, center for individualized medicine, Dr. Patricia LoRusso, mayo clinic, Mayo Clinic Proceedings


October 27, 2017

Searching for a genetic contributor to degenerative disk disease

By Sharon Rosen Sharon Rosen

Most people suffer from some type of back pain during their lifetime. That’s because there are many joints in the back that can degenerate over time. In many cases, back pain can be relieved without surgery. Ice packs, heat packs, physical therapy or injections can offer relief. However, for those who suffer from degenerative disk […]

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Tags: #CIMCon17, #degenerative disk disease, #DNA sequencing tests, #Dr. A. Noelle Larson, #Dr. Ahmad Nassr, #Dr. Andre van Wijnen, #Dr. Mohamad Bydon, #Dr. Wenchun Qu, #genomic profling, #genomic testing, #minimally invasive spine surgery, #targeted therapies


September 27, 2017

A genetic approach to cancer treatment

By Sharon Rosen Sharon Rosen

Article by Kristin Clift The medical community has historically defined and treated cancer based on where it is found in the body, such as the breast, lung or colon. So what has changed?  The FDA has recently started to approve treatments based on the genetic makeup of cancer rather than where the cancer is located. […]

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Tags: #cancer treatment, #CIMCon17, #DNA analysis, #Genetic Epidemiology and Risk Assessment Program, #Individualizing Medicine 2017, #targeted therapies, Advanced Cancer, cancer, center for individualized medicine, DNA Sequencing, Dr. Alexander Parker, Genetic Testing


September 25, 2017

Study evaluates effectiveness of deep genomic profiling in clinical setting

By Colette Gallagher Colette Gallagher

Genomic profiling is used today for patients with advanced cancers to help develop new ways to diagnose and treat their disease and offer an individualized treatment plan. While gene panel testing is relatively commonplace, there are many barriers to using new and more sophisticated DNA technologies. According to Mitesh Borad, M.D., an oncologist at the […]

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Tags: #cancer treatment, #CIMCon17, #Dr. Mitesh Borad, #genetic profiling, #Individualizing Medicine 2017, #long-insert whole genome, #Nature scientific Reports, #targeted therapies, #whole transcriptome sequencing, Advanced Cancer, center for individualized medicine, mayo clinic


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