Items Tagged ‘#targeted therapies’

August 15, 2019

Shaping the landscape of cancer care with precision therapies

By Sharon Rosen sharonhrosen

Article by Sara Damore Jeffrey Tyner, Ph.D., associate professor in the Department of Cell & Developmental Biology at Oregon Health & Science University, will join several precision cancer care leaders from across the country at the annual Individualizing Medicine Conference. Dr. Tyner will present “Precision Therapy through Functional Genomics in Hematologic Malignancies.” Dr. Tyner’s research […]

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Tags: #acute myeloid leukemia, #CIMCon19, #Dr. Jeffrey Tyner, #Functional Genomics, #targeted therapies, blood cancers, center for individualized medicine, genomics, hematolgic malignancies, Individualizing Medicine Conference 2019, mayo clinic, Oregon Health and Science University


June 10, 2019

Meet William Bobo, M.D. – taking the guesswork out of finding the right depression therapy

By Sharon Rosen sharonhrosen

Depression can touch every aspect of a person’s life – affecting the way they think, feel and behave. It is also the leading medical condition for those who complete suicide. Getting the right therapy is crucial. But for patients suffering from the disorder, finding an effective treatment often involves trial and error. That’s because it […]

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Tags: #Artificial Intelligence, #Center for Individualized Mediicine, #Dr. Arjun Athreya, #Dr. William Bobo, #individualized mediicne, #Mayo Clinic and Illinois Alliance for Technology-Based Healthcare, #mood disorders, #predictive algorithm, #selective serotonin reuptake inhibitors, #targeted therapies, #Treatment response, antidepressants


May 7, 2019

Targeting bile duct cancer – meet Mitesh Borad, M.D.

By Sharon Rosen sharonhrosen

The search for treatment targets for patients with bile duct cancer, also known as cholangiocarcinoma, has taken a 360 degree turn, offering new hope for patients. That’s according to Mitesh Borad, M.D., deputy director for Center for Individualized Medicine Biomarker Discovery Program at Mayo Clinic’s Arizona campus, Dr. Borad and his colleagues are using new […]

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Tags: #Dr. Mitesh Borad, #liver cancer, #targeted therapies, bile duct cancer, Biomarker Discovery Program, cholangiocarcinoma, fibroblast growth factor receptor (FGFR) inhibitors, Genetic Testing, genomics, Liquid biopsy, mayo clinic, Mayo Clinic Center for Individualized Medicine


July 2, 2018

A clearer picture: new imaging technologies advance diagnosis, individualized care

By Sharon Rosen sharonhrosen

When treating patients with cancer, one of the most challenging questions that physicians face is determining whether a tumor should be surgically removed immediately, or if it can be monitored over the course of time without performing surgery. Imaging tests – such as a CT scan or MRI – are essential tools that clinicians rely […]

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Tags: #Artificial Intelligence, #CIMCon18, #disease prediction, #Dr. Gabriel Krestin, #Dr. Kiaran McGee, #imaging biomarkers, #imaging tests, #Individualizing Medicine 2018: Advancing Care Through Genomics, #targeted therapies, individualized medicine, mayo clinic


February 13, 2018

New international practice guidelines for using tamoxifen to treat breast cancer

By Colette Gallagher colettegallagher

An international group of clinicians and scientists representing the Clinical Pharmacogenetics Implementation Consortium (CPIC) published the first-ever clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy in Clinical Pharmacology and Therapeutics. Tamoxifen is a hormonal agent used for the prevention and treatment of premenopausal and postmenopausal breast cancer that is estrogen receptor positive. […]

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Tags: #CIMCon18, #clinical guidelines, #Clinical Pharmacogenetics Implementation Consortium, #CYP2D6 geneotype, #estrogen receptor positive breast cancer, #tamoxifen, #targeted therapies, breast cancer, center for individualized medicine, DNA Sequencing, Dr. Matthew Goetz, Genetic Testing


November 7, 2017

Twenty-first century precision medicine cancer care

By Sharon Rosen sharonhrosen

As genomic sequencing has become faster and less expensive, physicians have used this new technology to guide and manage care for patients with cancer. Genomic testing, also known as genomic profiling, was initially used for patients with advanced cancer when standard therapy failed. The goal of the testing was to identify unique genetic characteristics of […]

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Tags: #cancer treatment, #Dr. Mitesh Borad, #genetic panel tests, #Genomic profiling, #targeted therapies, #tissue biopsy, #tumor sequencing, cancer, center for individualized medicine, Dr. Patricia LoRusso, mayo clinic, Mayo Clinic Proceedings


October 27, 2017

Searching for a genetic contributor to degenerative disk disease

By Sharon Rosen sharonhrosen

Most people suffer from some type of back pain during their lifetime. That’s because there are many joints in the back that can degenerate over time. In many cases, back pain can be relieved without surgery. Ice packs, heat packs, physical therapy or injections can offer relief. However, for those who suffer from degenerative disk […]

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Tags: #CIMCon17, #degenerative disk disease, #DNA sequencing tests, #Dr. A. Noelle Larson, #Dr. Ahmad Nassr, #Dr. Andre van Wijnen, #Dr. Mohamad Bydon, #Dr. Wenchun Qu, #genomic profling, #genomic testing, #minimally invasive spine surgery, #targeted therapies


September 27, 2017

A genetic approach to cancer treatment

By Sharon Rosen sharonhrosen

Article by Kristin Clift The medical community has historically defined and treated cancer based on where it is found in the body, such as the breast, lung or colon. So what has changed?  The FDA has recently started to approve treatments based on the genetic makeup of cancer rather than where the cancer is located. […]

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Tags: #cancer treatment, #CIMCon17, #DNA analysis, #Genetic Epidemiology and Risk Assessment Program, #Individualizing Medicine 2017, #targeted therapies, Advanced Cancer, cancer, center for individualized medicine, DNA Sequencing, Dr. Alexander Parker, Genetic Testing


September 25, 2017

Study evaluates effectiveness of deep genomic profiling in clinical setting

By Colette Gallagher colettegallagher

Genomic profiling is used today for patients with advanced cancers to help develop new ways to diagnose and treat their disease and offer an individualized treatment plan. While gene panel testing is relatively commonplace, there are many barriers to using new and more sophisticated DNA technologies. According to Mitesh Borad, M.D., an oncologist at the […]

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Tags: #cancer treatment, #CIMCon17, #Dr. Mitesh Borad, #genetic profiling, #Individualizing Medicine 2017, #long-insert whole genome, #Nature scientific Reports, #targeted therapies, #whole transcriptome sequencing, Advanced Cancer, center for individualized medicine, mayo clinic


September 19, 2017

How does a genomic tumor board impact patient care?

By Colette Gallagher colettegallagher

The outcomes from a Mayo Clinic study published in Oncotarget found value in having an established genomic tumor board, and using genomics for certain patients. The experience of the Genomic Tumor Board has promoted an evolution in the practice according to Alan Bryce, M.D., a Mayo Clinic oncologist, and co-first author on the study. “There […]

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Tags: #cancer treatment, #CIMCon17, #Dr. Jan Egan, #genetic testing fees, #Genomic analysis, #Genomic Tumor Board, #Individualizing Medicine 2017, #targeted therapies, Advanced Cancer, cancer, center for individualized medicine, Dr. Alan Bryce


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