July 7th, 2015 · Leave a Comment

Learn About Precision Medicine at Patient and Public Symposium

By Jeff Briggs

Brochure CoverPrecision medicine — or individualized medicine, as it is often called at Mayo Clinic — has been at the forefront of health care news in recent months. But what does it mean, why does it matter, and how does it affect you?

To answer these questions, and many more that you may have, Mayo Clinic’s Center for Individualized Medicine is offering a Patient and Public Symposium on September 20, from noon to 4 p.m., in Rochester, Minn.

Health care is changing rapidly and the impact on patients and families of individualized medicine will be profound. Genomic medicine is increasingly being used to help people live healthier lives, get the [...]

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Tags: Center for Individualized Medicine, genomics, Individualizing Medicine Conference 2015, Mayo Clinic, personalized medicine, precision medicine

July 3rd, 2015 · Leave a Comment

"21st Century Cures Act": Much Needed Legislation

By Jeff Briggs

Colorado Democrat Diana DeGette is one of the main sponsors of the 21st Century Cures bill

Colorado Democrat Diana DeGette is one of the main sponsors of the 21st Century Cures bill

“An ambitious bipartisan plan to accelerate medical innovation in the U.S. is moving ahead in a Congress famous for political gridlock,” writes The Lancet's Washington correspondent Susan Jaffe.

After a 12-year slide in federal funding for basic medical research, the Energy and Commerce Committee of the House of Representatives decided to take on that challenge by launching an initiative called 21st Century Cures. Fred Upton, a Republican from Michigan, and Diana DeGette, a Democrat from Colorado, co-authored the legislation. In [...]

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Tags: 21st Century Cures Act, Center for Individualized Medicine, FDA, NIH, precision medicine, Rep Diana DeGette, Rep Fred Upton, Susan Jaffe

July 1st, 2015 · Leave a Comment

From Bench to Bedside: How Precision Medicine is Changing the Future

By Jeff Briggs

Precision medicine is the opposite of one-size-fits-all therapy. An emerging approach to preventing or treating diseases, it factors in individual variability in genes, environment, and lifestyle in order to custom-tailor treatment. Although it is still far from becoming a routine part of clinical medicine, the Precision Medicine Initiative unveiled by President Barack Obama in January 2015 is designed to accelerate progress, initially in cancer and eventually in countless other diseases.

Dr. John Noseworthy

Dr. John Noseworthy

This was one of the topics at this year’s Aspen Ideas Festival, with its second annual “Spotlight on Health” program. Mayo Clinic was represented at the session by CEO John Noseworthy, M.D., [...]

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Tags: Aspen Ideas Festival, Dr Francis Collins, Dr John Noseworthy, Individualized Medicine, personalized medicine, precision medicine, Precision Medicine Initiative

June 25th, 2015 · Leave a Comment

Conquering Cancer: New Strategies through Individualized Medicine

By Jeff Briggs

Panel 4Everyone’s life has been affected by cancer. Everyone’s. Many people are cancer survivors. Others are family or friends of someone who has fought the disease. But nobody has escaped the terrible burden cancer brings to our lives.

Perhaps this is why so many physicians and researchers around the world have dedicated their lives to eradicating cancer.

Cancer is a disease of the genome and as more is learned about cancer tumors, the more we are finding that each tumor has its own set of genetic changes. Cancer genomics aims to advance personalized medicine through the DNA sequencing and analysis of patient tumors to better understand the genetic changes that are in cancer [...]

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Tags: cancer, Center for Individualized Medicine, DNA sequencing, Dr Edison Liu, Dr Patricia LoRusso, Genome Sequencing, Individualized Medicine, Individualizing Medicine Conference 2015, Mayo Clinic, precision medicine

June 22nd, 2015 · Leave a Comment

Mayo Clinic and TGen Help Launch Clinical Trials to Combat Advanced Skin Cancer

By Jeff Briggs

MC AZ outside

Mayo Clinic Arizona

With the advent of the Human Genome Project, it has become possible to completely sequence the DNA of a patient or his or her tumor. This technique has the potential to allow physicians to identify a tumor's unique vulnerabilities, or even to predict which tumors will recur or which may be benign enough that no treatment is required. These methods may allow cancer research to progress beyond the era of massive, take-all-comers clinical trials to an era in which every patient receives treatment that is precisely directed at the individual cancer's most vulnerable point.

Genomic oncologist Alan Bryce, M.D., studies cancer genetics and novel therapeutics [...]

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Tags: cancer, Center for Individualized Medicine, Dr Alan Bryce, Dr Aleksandar Sekulic, Dr Jeffrey Trent, genomics, Individualized Medicine, Mayo Clinic Arizona, Melanoma, Metastatic melanoma, personalized medicine, precision medicine, TGen

June 19th, 2015 · Leave a Comment

Molecular Classification May Improve Method Used to Diagnose and Treat Gliomas

By Jeff Briggs

malignant_glioma_cells-8col

Malignant glioma cells called glioblastoma multiforme cells. The cells have irregular shapes with fingers that can spread into the brain.

A glioma is a type of tumor that starts in the brain or spine. It is called a glioma because it arises from glial cells. Gliomas can affect your brain function and be life-threatening depending on their location and rate of growth. Gliomas make up about 30 percent of all brain and central nervous system tumors and a large percentage of all malignant brain tumors. Now, there’s good news coming out of Mayo Clinic Research about a molecular classification that could change and improve the methods that physicians rely on to determine prognosis [...]

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Tags: Center for Individualized Medicine, Dr Daniel LaChance, Dr Robert Jenkins, gliomas, Mayo Clinic, New England Journal of Medicine, precision medicine

June 17th, 2015 · 6 Comments

Dr. Keith Stewart Highlights the Discoveries and Looks at the Future of Genomic Medicine

By Jeff Briggs

Stewart, Keith.photo

Dr. Keith Stewart

Keith Stewart, M.B., Ch.B., recently appointed the Carlson and Nelson Endowed Director of the Center for Individualized Medicine, highlighted the latest discoveries in genomic research and illustrated them with patient stories to demonstrate the power of genomic medicine to supporters of Mayo Clinic’s fundraising campaign, “You Are . . . The Campaign for Mayo Clinic.” Then he presented where genomic research at Mayo Clinic is headed in the future.

Dr. Stewart is also the Vasek and Anna Maria Polak Professor of Cancer Research.

Here are some of the highlights of his talk:

Introduction

The Center for Individualized Medicine was started [...]

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Tags: biobank, bioethics, cancer, Center for Individualized Medicine, Dr Keith Stewart, Dustin Bennett, genomic medicine, Gianrico Farrugia, Individualized Medicine, Mayo Clinic, Pharmacogenetics, precision medicine

June 11th, 2015 · Leave a Comment

Forecasting Your Patient’s Future Health

By Jeff Briggs

Panel 5If you could provide access to your patients a list of every disease they would develop in their lifetime, would they read it? Would it read like their kitchen grocery list? Or would it contain the epic sweep of Moby Dick?

And what would they do if that list identified diseases that their children and grandchildren might inherit? Would they read on? Or would they close the book?

What if by identifying these diseases now, you could work with your patients to help prevent the disease from ever occurring, or to develop a treatment plan before the onset of clinical symptoms?

photo-main-stageWhile this may [...]

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Tags: Center for Individualized Medicine, Dr Stephen Friend, genomic medicine, genomics, Individualizing Medicine Conference 2015, Mayo Clinic, personalized medicine, precision medicine

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