July 31st, 2015 · Leave a Comment

Mayo Clinic Study Uncovers Key Differences Among ALS Patients

By Jeff Briggs Jeff Briggs

ALS cells

ALS cells

ALS, or amyotrophic laterals sclerosis, is a devastating disease for thousands of people in the country. Rapidly progressive, invariably fatal, ALS is a neurodegenerative disease that affects nerve cells in the brain and the spinal cord. It attacks the nerve cells responsible for controlling voluntary muscles (muscle action we are able to control, such as those in the arms, legs, and face).

A-myo-trophic comes from the Greek. "A" means no. "Myo" refers to muscle, and "Trophic" means nourishment – "No muscle nourishment." When a muscle has no nourishment, it "atrophies" or wastes away. "Lateral" identifies the areas in a person's spinal cord where portions of the nerve [...]

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Tags: ALS, ALS Ice Bucket Challenge, amyotrophic laterals sclerosis, Center for Individualized Medicine, Dr Hu Li, Dr Leonard Petrucelli, genomic medicine, Lou Gehrig's disease, Mayo Clinic Florida, RNA, RNA defects

July 29th, 2015 · Leave a Comment

Dr. George Vasmatzis Brings Biomarkers to New Audience in Talk at TEDxMinneapolis

By Jeff Briggs Jeff Briggs

George V TEDxboxTEDxMinneapolis is going to the brink. The independently organized TED event out of Minneapolis is hosting six speakers this Friday, July 31, who have faced head on radically new ideas, profound developments and significant dangers — all of which will change how we perceive our world in the near and long range future.

One of those speakers is George Vasmatzis, Ph.D., co-director of the Biomarker Discovery Program at the Mayo Clinic Center for Individualized Medicine. Dr. Vasmatzis will be introducing a new audience to the profound changes happening in health care with precision medicine, and how his work with biomarkers is ushering in massive changes to how we treat patients. [...]

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Tags: biomarkers, Cancer, Center for Individualized Medicine, Dr George Vasmatzis, precision medicine, TED talks, TEDxMinneapolis

July 24th, 2015 · Leave a Comment

Trailblazer Genomic Scientist to be Keynote Speaker at 2015 Individualizing Medicine Conference

By Jeff Briggs Jeff Briggs

j craig venterOne of the world's leading geneticists, J. Craig Venter, Ph.D., has innovated and infuriated in equal measure. He may be best known for being the first person to sequence his own genome, back in 2001, but his accomplishments in genomics reach far and wide—often with controversy attached.

Leaving Newport, Calif., and the Southern California surfing scene, Dr. Venter enlisted for a tour of duty in the U.S. Navy during the Vietnam War. Detecting more intelligence in him than his high school record indicated, the Navy trained him as a medical corpsman and assigned him to the Da Nang hospital.

"I was there during the Tet offensive," he said. "I got introduced to [...]

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Tags: Center for Individualized Medicine, DNA sequencing, Dr Francis Collins, genomic medicine, genomics, Individualized Medicine, J Craig Venter, personalized medicine, predictive medicine

July 21st, 2015 · Leave a Comment

Young Researchers Catching Waves with Mayo Clinic SURF Program

By Jeff Briggs Jeff Briggs

surf-400The Mayo Clinic Center for Individualized Medicine has a great group of interns working for it this summer. One of them, Shea Jennings, an intern in public affairs, files this report on two students from the University of Illinois at Urbana-Champaign who are interning in the CIM laboratories with the Summer Undergraduate Research Fellowship (SURF) Program.

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Young Researchers Catching Waves with Mayo Clinic SURF Program

M.D.s, Ph.D.s, M.D.-Ph.D.s, Pharm.D.s. Scan a list of Mayo Clinic researchers, and you might mistake it for alphabet soup. It’s no secret that Mayo attracts some of the brightest and best-educated minds in medicine. This summer, however, the Mayo Clinic Center for [...]

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Tags: Center for Individualized Medicine, Mayo Graduate School, Stephanie Youssef, SURF Program, Vivian Chu

July 16th, 2015 · Leave a Comment

Test for Diagnosing Fibrolamellar Carcinoma Yields 100-Percent Accuracy

By Jeff Briggs Jeff Briggs

Fibrolamellar Carcinoma-WPfusion gene is a hybrid gene formed from two previously separate genes. It can occur as a result of translocation, interstitial deletion or chromosomal inversion. Known to scientists since 1960, fusion genes can contribute to tumor formation because fusion genes can produce much more active abnormal protein than non-fusion genes. Often, fusion genes are oncogenes that cause cancer.

Presence of certain chromosomal aberrations and their resulting fusion genes is commonly used within cancer diagnostics in order to set a precise diagnosis. Chromosome banding analysis, fluorescence in situ hybridization (FISH), and reverse transcription polymerase chain reaction (RT-PCR) are common methods employed at the Mayo Medical Laboratories to detect fusion genes.
[...]

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Tags: Cancer, Center for Individualized Medicine, Dr Rondell Graham, Fibrolamellar Carcinoma, gene sequencing, genetic testing, precision medicine

July 13th, 2015 · Leave a Comment

Mayo Clinic CIM Director Dr. Keith Stewart Joins Washington Panel on Personalized Medicine 101

By Jeff Briggs Jeff Briggs

Stewart, Keith.photo

Dr. Keith Stewart

Keith Stewart, M.B., Ch.B., the Carlson and Nelson Endowed Director of the Mayo Clinic Center for Individualized Medicine, will be joining a panel of experts to speak this week in Washington, D.C., about ways to improve patient care in the 21st century.

The Office of Senator Amy Klobuchar (D-MN) has invited the Personalized Medicine Coalition (PMC) to organize a Capital Hill briefing on personalized medicine. The briefing, co-organized by PMC and the offices of Sens. Klobuchar and Orrin Hatch (R-UT), is designed to educate members of Congress about how growth in this field translates to improved health outcomes for patients and decreased costs for [...]

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Tags: Center for Individualized Medicine, Dr Keith Stewart, Individualized Medicine, personalized medicine, Personalized Medicine 101, precision medicine, Sen Amy Klobuchar, Sen Orrin Hatch

July 10th, 2015 · Leave a Comment

Precision Medicine Initiative: Planning Underway But No Funding

By Jeff Briggs Jeff Briggs

President Obama_1

President Barack Obama introducing the Precision Medicine Initiative

Funding for biomedical research and precision medicine has been much on our minds in recent weeks. Last week, we posted a blog on Susan Jaffe’s excellent story in The Lancet about the attempts to fund the 21st Century Cures Act. This week we again turn to Ms. Jaffe, The Lancet’s Washington correspondent, for her story on the Precision Medicine Initiative.

President Barack Obama unveiled the Precision Medicine Initiative in his annual State of the Union address in January. His goal with the initiative was to radically change the medical treatment patients receive in the U.S.

“I want the country that [...]

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Tags: Biomedical research, Center for Individualized Medicine, Dr Alexander Parker, Dr Robert Diasio, Individualized Medicine, National Press Foundation, precision medicine, Precision Medicine Initiative, President Barack Obama

July 7th, 2015 · Leave a Comment

Learn About Precision Medicine at Patient and Public Symposium

By Jeff Briggs Jeff Briggs

Brochure CoverPrecision medicine — or individualized medicine, as it is often called at Mayo Clinic — has been at the forefront of health care news in recent months. But what does it mean, why does it matter, and how does it affect you?

To answer these questions, and many more that you may have, Mayo Clinic’s Center for Individualized Medicine is offering a Patient and Public Symposium on September 20, from noon to 4 p.m., in Rochester, Minn.

Health care is changing rapidly and the impact on patients and families of individualized medicine will be profound. Genomic medicine is increasingly being used to help people live healthier lives, get the [...]

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Tags: Center for Individualized Medicine, genomics, Individualizing Medicine Conference 2015, Mayo Clinic, personalized medicine, precision medicine

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