July 22nd, 2014 · Leave a Comment

Earning the No. 1 Spot on U.S. News and World Report's Top Hospitals

By Center for Individualized Medicine

We are very excited to share the news of Mayo Clinic achieving the highest honor in U.S. News and World Report’s ranking of top hospitalsMayo Clinic earned more number one rankings than any other provider, ranking  number one or number two in 11 of the 12 specialties based on reputation, services and volumes, safety and clinical outcomes.

Here at the Center for Individualized Medicine, we strive to continue our research and implementation of individualized medicine from promise to practice. Individualized medicine, also known as personalized medicine or precision medicine, means tailoring diagnosis and treatment to each patient to optimize care. Patients have experienced this kind of care for [...]

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Tags: biobank, bioethics, biomarker, biomarkers, cancer, center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, Genetics, genome, genome science, Genome Sequencing, genomic medicine, genomics, individualized medicine, Mayo Clinic, personal genomics, personalized care, personalized medicine, pharmacogenomics, predictive medicine, whole genome sequencing

July 18th, 2014 · Leave a Comment

Personalized Medicine: The Changing Landscape of Health Care

By Center for Individualized Medicine

Speaking at the Individualizing Medicine Conference 2013, Edward Abrahams, Ph.D. presents on the changing landscape that genomics is creating throughout health care. Not only within the health care industry itself, the field of Individualized Medicine and the power that genomics brings, is also changing the way people in Washington D.C. think about the way it should interact and prepare for the future of health care.

Edward Abrahams, Ph.D. is president of the Personalized Medicine Coalition. Representing innovators, scientists, patients, providers and payers, the Personalized Medicine Coalition promotes the understanding and adoption of personalized medicine concepts, services and products for the benefit of patients and the health system. It has grown from its original [...]

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Tags: DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, Genetics, genome, genome science, Genome Sequencing, genomic medicine, genomics, individualized medicine, Mayo Clinic, personal genomics, personalized care, personalized medicine, predictive medicine, whole genome sequencing

July 15th, 2014 · Leave a Comment

Genome-Wide Associations of Citalopram and Escitalopram Plasma Drug and Metabolite Concentrations

By Center for Individualized Medicine

 

Pharmacogenomic Publication

 

Published in the British Journal of Clinical Pharmacology, a team of researchers from the Mayo Clinic, led by the director of the Center for Individualized Medicine's Pharmacogenomics Program, Richard Weinshilboum, M.D., applied a genome-wide association study (GWAS) to identify genetic factors that contribute to variation in plasma concentrations of Citalopram (CT) or escitalopram (S-CT), and their metabolites in Major Depressive Disorder (MDD) patients treated with CT or S-CT.

The GWAS was performed using samples from 435 MDD patients. Linear mixed models were used to account for within-subject correlations of longitudinal measures of plasma drug/metabolite concentrations (4 and [...]

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Tags: center for individualized medicine, citalopram, DNA, DNA Sequencing, dna test, DNA Testing, escitalopram, gene sequencing, genetic, Genetics, genome, genome science, Genome Sequencing, genomic medicine, genomics, individualized medicine, major depressive disorder, Mayo Clinic, personal genomics, personalized care, personalized medicine, plasma drug concentrations, predictive medicine, SSRI, whole genome sequencing

July 10th, 2014 · Leave a Comment

Individualized Medicine Grand Rounds Released

By Center for Individualized Medicine

CIM Video

 

Mayo Clinic has now made its video education medical grand rounds lectures and clinical presentations accessible in the new online medical professional video center.

These lectures contain new practice procedures, treatment options and research covering a wide variety of specialties., including a video lecture on Choline C-11 treatment for recurrent prostate cancer, and fecal microbiota transplant, providing step-by-step details of how the procedure is completed so providers and patients can see the process from beginning to end.

 

You can view all videos related to Individualized Medicine on our channel here.

 

 
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Tags: bioethics, biomarker, biomarkers, cancer, center for individualized medicine, DNA, dna test, DNA Testing, gene sequencing, Genetics, genome science, Genome Sequencing, genomic medicine, genomics, individualized medicine, individualized Medicine clinic, IndividualizedMedicine, Mayo Clinic, personal genomics, personalized care, personalized medicine, predictive medicine, whole genome sequencing

July 8th, 2014 · Leave a Comment

Missouri is 19th State Signing Breast Density Bill into Law

By AJ Montpetit

As of today, women in 31 states leave their yearly mammogram appointment without the knowledge of their own breast density number. This single data point is important in tailoring personalized care for each woman, and assisting in possible further preventative care.

Are You Dense, Inc. released a press release announcing the passing of the 19th state bill, which made into law in the state of Missouri, to include breast density information in a patient's mammography reporting results.
"Too many women are unaware of the effects of breast density, but this knowledge can save lives by leading to earlier breast cancer detection," notes Representative Sue Allen of Missouri.
Hitting closer to home here at the Center for Individualized Medicine,

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Tags: Are You Dense, biomarker, biomarkers, breast cancer, breast density, cancer, center for individualized medicine, DNA Sequencing, dna test, DNA Testing, gene sequencing, Genetics, genome, genome science, Genome Sequencing, genomic, genomic medicine, genomics, individualized medicine, mammogram, mammography, Mayo Clinic, Nancy Cappello, Nancy Cappello PhD, personalized care, personalized medicine, predictive medicine, whole genome sequencing

July 3rd, 2014 · Leave a Comment

Mayo Clinic Researchers Reveal New Genes Key to Kidney Cancer

By Center for Individualized Medicine

Genomic Revelation
A genomic analysis of clear cell renal cell carcinoma (ccRCC), the most common form of kidney cancer, from 72 patients has uncovered 31 genes that are key to development, growth and spread of the cancer, say researchers from Mayo Clinic in Florida. Eight of these genes had not been previously linked to kidney cancer, and six other genes were never known to be involved in any form of cancer.

 

 

Their study, in the journal Oncotarget, is the most extensive analysis to date of gene expression’s role in ccRCC tumor growth and metastasis. The ccRCC subtype accounts for 80 percent of [...]

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Tags: cancer, center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic, Genetics, genome science, Genome Sequencing, genomic, genomic medicine, genomics, individualized medicine, individualized Medicine clinic, Mayo Clinic, personal genomics, personalized care, personalized medicine, predictive medicine, whole genome sequencing

July 1st, 2014 · Leave a Comment

Biomarkers 101 Part 2

By AJ Montpetit

Biomarkers 101 Part 2

 

 

George Vasmatzis, Ph.D., and John Cheville, M.D., co-directors of the Biomarker Program at the Center for Individualized Medicine at Mayo Clinic, introduce us to the world and work of Biomarkers.

The Biomarker Discovery Program is a multidisciplinary team that includes oncologists, surgeons, pathologists, molecular biologists, bioengineers, bioinformaticians and others. By combining expertise, the program takes a clinical question, and answers it through a four-phase approach: Discovery, experimental validation, preclinical validation and clinical validation.

The Co-Directors answer the following three questions in this video:

  1. How do you identify a Biomarker?
  2. What projects are you currently working on?
  3. What [...]

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Tags: biomarker, Biomarker Discovery Program, biomarkers, bladder cancer, breast cancer, center for individualized medicine, dna test, DNA Testing, gene sequencing, genome science, genomic medicine, genomics, HER2, individualized medicine, John Cheville, Modern Pathology, personal genomics, personalized medicine, predictive medicine

June 26th, 2014 · Leave a Comment

Non-Hodgkin Lymphoma New Routine Testing

By AJ Montpetit

Article Originally Featured on the Mayo Clinic News Network.

A Mayo Clinic-led group of researchers has discovered three subgroups of a single type of non-Hodgkin lymphoma that have markedly different survival rates. These subgroups could not be differentiated by routine pathology but only with the aid of novel genetic tests, which the research team recommends giving to all patients with ALK-negative anaplastic large-cell lymphoma (ALCL). Findings are published in the journal Blood.

 

 

Patients whose lymphomas had TP63 rearrangements had only a 17 percent chance of living five years beyond diagnosis, compared to 90 percent of patients whose tumors had [...]

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Tags: cancer, center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, Genetics, genome, genome science, Genome Sequencing, genomic, genomic medicine, genomics, individualized medicine, Mayo Clinic, personal genomics, personalized care, personalized medicine, predictive medicine, whole genome sequencing

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